Realization and Properties of Biochemical-Computing Biocatalytic XOR Gate Based on Enzyme Inhibition by a Substrate

نویسندگان

  • Jan Halamek
  • Vera Bocharova
  • Mary A. Arugula
  • Guinevere Strack
  • Vladimir Privman
  • Evgeny Katz
چکیده

We consider a realization of the XOR logic gate in a process biocatalyzed by an enzyme which can be inhibited by a substrate when the latter is inputted at large enough concentrations. A model is developed for describing such systems in an approach suitable for evaluation of the analog noise amplification properties of the gate. The obtained data are fitted for gate quality evaluation within the developed model, and we discuss aspects of devising XOR gates for functioning in "biocomputing" systems utilizing biomolecules for information processing.

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عنوان ژورنال:
  • The journal of physical chemistry. B

دوره 115 32  شماره 

صفحات  -

تاریخ انتشار 2011